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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
4.55
Human Site:
T49
Identified Species:
7.69
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
T49
T
G
S
P
W
P
G
T
A
A
P
A
A
S
Y
Chimpanzee
Pan troglodytes
XP_508221
618
67613
T139
T
G
S
P
W
P
G
T
A
A
P
A
A
S
Y
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
N40
N
L
T
L
N
K
A
N
S
G
K
N
D
D
K
Dog
Lupus familis
XP_855547
495
55650
D44
R
R
Q
S
L
I
E
D
A
R
K
E
R
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
E43
G
R
R
Q
S
L
I
E
D
A
R
K
E
R
E
Rat
Rattus norvegicus
P04177
498
55948
E43
G
R
R
Q
S
L
I
E
D
A
R
K
E
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
P58
N
G
N
P
S
T
F
P
M
S
P
R
L
P
G
Chicken
Gallus gallus
P70080
445
51121
Frog
Xenopus laevis
Q92142
481
55388
E30
D
E
N
Q
I
N
N
E
F
N
K
S
T
Y
I
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
L39
F
V
G
R
R
Q
S
L
I
E
D
A
R
K
E
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
E26
L
I
D
D
A
R
R
E
R
S
S
S
S
E
G
Fruit Fly
Dros. melanogaster
P18459
579
65977
E111
D
V
E
F
E
S
V
E
Q
E
Q
S
E
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
F45
F
E
K
L
S
K
S
F
D
D
M
S
F
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
0
6.6
N.A.
6.6
6.6
N.A.
20
0
0
6.6
0
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
13.3
6.6
N.A.
6.6
6.6
N.A.
33.3
0
13.3
6.6
20
13.3
N.A.
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
22
29
0
22
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
8
8
0
0
0
8
22
8
8
0
8
8
0
% D
% Glu:
0
15
8
0
8
0
8
36
0
15
0
8
22
15
22
% E
% Phe:
15
0
0
8
0
0
8
8
8
0
0
0
8
0
0
% F
% Gly:
15
22
8
0
0
0
15
0
0
8
0
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
8
15
0
8
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
0
15
0
0
0
0
22
15
0
8
15
% K
% Leu:
8
8
0
15
8
15
0
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% M
% Asn:
15
0
15
0
8
8
8
8
0
8
0
8
0
0
0
% N
% Pro:
0
0
0
22
0
15
0
8
0
0
22
0
0
8
0
% P
% Gln:
0
0
8
22
0
8
0
0
8
0
8
0
0
0
8
% Q
% Arg:
8
22
15
8
8
8
8
0
8
8
15
8
15
15
0
% R
% Ser:
0
0
15
8
29
8
15
0
8
15
8
29
8
22
0
% S
% Thr:
15
0
8
0
0
8
0
15
0
0
0
0
8
0
0
% T
% Val:
0
15
0
0
0
0
8
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _